New viruses have recently been discovered, affecting both rats and mice. Both can lead to disease and death in immunodeficient rodents. Don’t compromise your research due to new, prevalent viruses.
Mouse Kidney Parvovirus (aka Murine Chappapovirus) is a recently discovered parvovirus, divergent from MMV and MPV, affecting the kidneys of immunocompromised mice. MKPV has a prevalence of >5% in research institutions, with a higher prevalence in wild mice. Clinical manifestations include elevated creatinine and BUN, kidney fibrosis and necrosis. MKPV Is transmitted via direct contact, bedding, feces and urine. Several sample types are acceptable for testing: fecal pellets, environmental samples, mouse tissues, cell lines and tumors.
Rat Polyoma virus is a recently discovered virus of the Polyoma family and related to the WU and KI polyomavirus associated with acute respiratory symptoms in children. RPyV2 has prevalence of >32% in research institutions. Clinical manifestations show respiratory distress and a reduction in fecundity.RPyV2 is transmitted via direct contact, bedding, and fomites. Several sample types are acceptable for PCR testing: fecal pellets, environmental samples, oral swabs and tissues.